Epigenomics and Genomics

Editorial: Genomics and Epigenomics of Tumor and Aging Cells

It is well established that aberrant DNA methylation, as well as genetic heterogeneity are the hallmarks of malignancies. More recently, it was shown that similar features are accompanying many degenerative processes and in particular aging. However, distinct specific processes of malignant transformation or aging may be characterized by the different changes within particular cell genomics and...

Glycomics meets genomics, epigenomics and other high throughput omics for system biology studies.

Majority of eukaryotic proteins are glycosylated and their glycan moieties have numerous important structural, functional and regulatory roles. Because of structural complexity of glycans and technological limitations glycomics, and particularly glycoproteomics was not able to follow rapid progress in genomics and proteomics over last 30 years. However, the field of glycan has been progressing ...

Editorial Introduction: Epigenomics and Prevalent Skeletal Disorders

Precision Medicine: A New Revolution in Healthcare System

Every human being is different based on genetics, lifestyle, and environmental factors. Novel medical technologies have become more precise owing to molecular information, including genomics, transcriptomics, proteomics, metabolomics, etc. The “omics” technologies have opened up new horizons for healthcare systems, enabling them to prevent and/or diagnose diseases more precisel...

Cancer epigenomics: beyond genomics.

For many years cancer research has focused on genetic defects, but during the last decade epigenetic deregulation has been increasingly recognized as a hallmark of cancer. The advent of genome-scale analysis techniques, including the recently developed next-generation sequencing, has enabled an invaluable advance in the molecular mechanisms underlying tumor initiation, progression, and expansio...